Derma-Cosmetic Filler for At-Home Use
Fillerina® is a revolutionary, no-needle, dermo-cosmetic filler for at-home use that contains the first-ever blend of six hyaluronic acids with different weights and structures to facilitate in the plumping of tissues without puncturing the skin. Featuring a patent for the formula containing the six different molecular structures of varying weights and size of hyaluronic acid (Swiss Patent CH 705713) and a patent for the precision applicator (Swiss Patent CH 695412), Fillerina® is the only cosmetic product that allows large quantities of hyaluronic acid to penetrate deep into the cutaneous tissues, without injections.
Launching in the US in March 2016 and available in three graded concentrations, Swiss created Fillerina®, which contains a unique formula of a very high quantity of hyaluronic acids and peptides to soften fine lines and wrinkles and increase tissue volume in cheeks and lips. Available in a 14-day intensive treatment and everyday maintenance products, Fillerina® has been clinically proven to work effectively via a double-blind, randomized clinical trial.*
Fillerina® 14 Day Treatment
* 14 doses of 2ml of gel filler
* 14 doses of 2ml nourishing film
* 2 precision applicators
Dosages of Active Ingredients
Fillerina® dermo-cosmetic fillers are available in three different concentrations in order to provide the most effective and suitable treatment for the skin on the face and neck.
▪ Grade 1 – Treats moderate wrinkles and expression lines, and improves signs of sagging, particularly around the lips and cheekbones.
▪ Grade 2 – Treats visible wrinkles and expression lines and improves uneven skin tone and areas of visible sagging especially around the cheekbones and lips.
▪ Grade 3 – Treats deep set wrinkles and expression lines, very uneven skin tone and severe sagging of facial features, especially around the lips and cheekbones.
Efficacy on Wrinkles – Cheekbones – Lips
Fillerina® dermo-cosmetic filler was tested in an in-vivo, double blind, placebo controlled study that has been carried out on 40 women*. Measurements determined not only the decrease in terms of wrinkle depth and volume, but also the increase in the volume of cheekbones and lips and the lifting of facial features:
Reduction of Wrinkle Depth
The wrinkle depth is the linear measurement of the skin surface at the innermost point, expressed in micro-millimetres.
The filling action of Fillerina reduces wrinkle depth by an average of 21.8%, and up to 54.8%.
Filling of Wrinkle Volume
The wrinkle volume is represented by the empty space left by the depressions of the wrinkles and furrows, measured in mm3.
The Fillerina effect allows decreasing the volume of the wrinkle by an average of 26.3%, and up to 48.8%, filling the empty space.
Lifting of Facial Features:
Average: -1.32 mm
Up to: -2,87 mm
The data measure the distance between the upper part (front) and lower part of the face (jawline) in 5 points and are expressed in millimeters. Negative number = reduction in distance = remodeling action of the oval.
Increase of Cheekbone Volume:
Average: +2,27 mm
Up to: +3,39 mm
The data measure the variation in the distance between the contours of the cheekbones and a line tangent to the nose, expressed in millimeters.
Lifting of Cheekbones:
Average: -2,51 mm
Up to: -3,67 mm
The measurement of the cheekbone lift is a reduction (in millimeters) of the distance between the contours of the cheekbones and a horizontal line intersecting the eyes.
Increase in Lip Volume:
The treatment with Fillerina active ingredient results in an increase in the volume of the lips at all times. After 3 hours since the first application, an increase of +8.5% was already reported. At 30 days the average increase is of 14,2% up to 44,7%.
Key Ingredients and Benefits
Fillerina® dermo-cosmetic fillers feature a blend of six different hyaluronic acid molecules which vary in size and weight in order to most effectively penetrate and plump up the skin.
Hyaluronic Acid (1000 Da) – Immediately penetrates the skin and helps with the swelling of tissues and the smoothing of wrinkles.
Hydrolyzed Sodium Hyaluronate (5000 Da) – As above.
Hydrolyzed Hyaluronic Acid (50.000 Da) – Penetrates the middle and deep layers of the skin, filling in wrinkles and plumping up lines from the inside.
Sodium Hyaluronate (200.000 Da) – Penetrates the surface and middle layers of the skin binding large quantities of water and helps level out the cutaneous skin layer.
Sodium Hyaluronate (2.000.000 Da) – Penetrates the surface layers of the skin and helps to keep tissue plumped up.
Sodium Hyaluronate Crosspolymer (Reticulated Hyaluronic Acid) – Guarantees a slow and continual hyaluronic acid release into the skin, helping to keep the skin tissue plumped up.
Matrixyl – Provides reconstruction and gradual progressive plumping up of cutaneous tissue.
Hexapeptide – Stimulates the production of membrane proteins to help the flow of water through all of the skin’s layers.
The penetration tests on the different HA have been carried out by means of the experimental system known as Franz Diffusion Cells.
The Fillerina® treatment must be used once a day, in the morning or in the evening, every day for 14 days.
Directions For Use
The application of the Fillerina® 1 (Replenishing filler gel) is made using the special applicator, which allows for 1ml (0,03 FL. OZ.) amounts of product to be drawn and released accurately into the desired areas. The gel filler should be left to work for 10 minutes to allow the active ingredients to fill the desired areas. The palm of the hand should be used to allow residual product to penetrate the skin. Suggested quantity for each application: 2ml (0,07 FL. OZ.).
The Fillerina® 2 (Nourishing Film) is applied to ensure a sufficient amount of moisturizing and nourishing substances and allows the filler application to be completed with the maximum amount of comfort.
Directions For Use
1-2ml of the nourishing film is extracted and applied all over the face and neck. It is important to be hydrated when using this product as this will optimise the effectiveness of the treatment.
Fillerina® 14 Day Treatment Pricing
Grade 1 – $150.00, 2x30ml / 1.0 FL. OZ.
Grade 2 – $165.00, 2x30ml / 1.0 FL. OZ.
Grade 3 – $175.00, 2x30ml / 1.0 FL. OZ.
Fillerina® Daily Treatments
Fillerina® day treatments are also available in three doses and are specifically created for the day time and night time and to target the eye area and lips.
Fillerina® Day Cream
The day cream contains the same ingredients as the gel filler including the 6 patented HA molecules, designed for maintenance following the gel treatment. The cream contains ingredients to nourish and moisturize the skin whilst also providing anti-aging benefits.
Tube 50 ml / 1.7 FL. OZ.
Fillerina® Night Cream
The night cream contains the 6 HA molecules and the same peptides in in the gel filler. It also contains nourishing ingredients that promote skin regeneration overnight such as Shea Butter, Wheat Germ Oil, Sweet Almond Oil, Rose Hip Seed Oil, Vitamin E & Tree Fern Extract. Yeast Extract stimulates sluggish skin repair cells and Salicylic Acid dissolves dead skin cells. Daily use will enhance the results of the treatment. The creams contain a proportional quantity of HA.
Tube 50 ml / 1.7 FL. OZ.
Fillerina® Eye and Lip Cream
The cream also contains the 6 hyaluronic acid molecules and is rich in oils such as Rice Bran Oil, Sweet Almond Oil & Vitamin E to improve the skin in the delicate eye area. It also contains nourishing ingredients and collagen-stimulant peptides. The creams contain a proportional quantity of HA which fills in the fine lines and acts as a plumping agent.
Tube 15 ml / 0.5 FL. OZ.
Prices Day Night Eye-Lips
Grade 1 $90 $110 $75
Grade 2 $105 $125 $90
Grade 3 $120 $140 $110
Fillerina® is owned by the brand Labo. Labo consists of two different companies: the Swiss one, named Labo Cosprophar AG, with headquarters in Basel, and the Italian one, named Labo International srl, with headquarters in Padua (Italy).
The combined mission of these two companies is to make important investments in research, design and manufacture of high value-added cosmetic formulations for the consumer and after verifying the reception of the product by the Italian market to promote its international distribution in Europe and worldwide.
Fillerina® Swiss Patent CH 705713
Derma-Cosmetic Precision Applicator
Swiss Patent CH 695412
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